Seaweeds and Corals from the Brazilian Coast: Review on Biotechnological Potential and Environmental Aspects.

Brazil has a megadiversity that includes marine species that are distributed along 800 km of shoreline. This biodiversity status holds promising biotechnological potential. Marine organisms are important sources of novel chemical species, with applications in the pharmaceutical, cosmetic, chemical, and nutraceutical fields. However, ecological pressures derived from anthropogenic actions, including the bioaccumulation of potentially toxic elements and microplastics, impact promising species. This review describes the current status of the biotechnological and environmental aspects of seaweeds and corals from the Brazilian coast, including publications from the last 5 years (from January 2018 to December 2022). The search was conducted in the main public databases (PubChem, PubMed, Science Direct, and Google Scholar) and in the Espacenet database (European Patent Office-EPO) and the Brazilian National Property Institute (INPI). Bioprospecting studies were reported for seventy-one seaweed species and fifteen corals, but few targeted the isolation of compounds. The antioxidant potential was the most investigated biological activity. Despite being potential sources of macro- and microelements, there is a literature gap regarding the presence of potentially toxic elements and other emergent contaminants, such as microplastics, in seaweeds and corals from the Brazilian coast.

Urban Soil Pollution by Heavy Metals: Effect of the Lockdown during the Period of COVID-19 on Pollutant Levels over a Five-Year Study

When residents of Volos, a city in central Greece, are trying to recall their daily life after the end of the quarantine due to COVID-19, the soil pollution survey provided valuable insights, which are compared with a 4-year study carried out in that area before the pandemic period. Using appropriate indices, namely contamination factor (CF), pollution load index (PLI), geo-accumulation index (Igeo), ecological risk factor (Er), and potential ecological risk index (RI), and using geostatistical tools, maps were constructed for each metal (Cu, Zn, Pb, Ni, Cd, Co, Cr, Mn). Variations in the values of the contamination indices showed a significant redistribution in pollutant load from areas previously polluted by high vehicle traffic and the activities of the main port to the residential areas, where the habitants have their homes and playgrounds. The study showed that Cu, Zn, Pb, and Co concentrations increased during the pandemic period by 10%, 22.7%, 3.7%, and 23.1%, respectively. Ni's concentration remained almost constant, while Cd, Cr, and Mn concentrations were decreased by 21.6%, 22.2%, and 9.5%, respectively. Fluctuations in the concentrations and corresponding contamination and ecological indices of the elements can serve as a means for highlighting potential sources of pollution. Therefore, although the pandemic period created anxiety, stress, and economic hardship for citizens, it may prove to be a valuable tool for investigating the sources of pollution in urban soils. The study of these results could potentially lead to optimal ways for managing the environmental crisis and solve persistent problems that pose risks to both the soil environment and human health. © 2023 by the authors.

The concentrations of essential/toxic elements in serum of COVID-19 patients are not directly related to the severity of the disease.

BACKGROUND: In recent months, the current COVID-19 pandemic has generated thousands of studies directly or indirectly related with this disease and/or the coronavirus SARS-CoV-2 causing the infection. On August 22, 2022, the database PUBMED included 287,639 publications containing the term COVID-19. However, in spite of the importance of trace elements in human health, including the immune system, data on the levels of metals/metalloids in COVID-19 patients is very limited. METHODS: The concentrations of As, Cd, Cr, Cu, Hg, Fe, Mg, Mn, Pb, Se, V and Zn were determined by inductively coupled plasma-mass spectrometry (ICP-MS) in 126 serum samples of individuals infected with SARS-CoV-2, as well as in 88 samples of non-infected individuals. Participants were divided into four groups: i) individuals COVID-19 positive (COVID-19 +) with an asymptomatic infection course; ii) individuals suffering mild COVID-19; iii) individuals suffering severe COVID-19, and iv) individuals COVID-19 negative (COVID-19-) (control group). The occurrence of the analyzed metals/metalloids was evaluated along with the biochemical profile, including blood cell counts, lipids, proteins and crucial enzymes. RESULTS: Serum levels of Mg, V, Cr, Cu, Cd, and Pb were higher in COVID-19 positive patients than those in the control group. Although no significant differences were observed between the different groups of patients, the concentrations of Cd, Pb, V and Zn showed a tendency to be higher in individuals with severe COVID-19 than in those showing mild symptoms or being asymptomatic. Arsenic and Hg were rarely detected, regardless if the subjects were infected by SARS-CoV-2, or not. The current results did not show significant differences in the levels of the rest of analyzed elements according to the severity of the disease (asymptomatic, mild and severe). CONCLUSIONS: In spite of the results here obtained, we highlight the need to reduce the exposure to Cd, Pb and V to minimize the potential adverse health outcomes after COVID-19 infection. On the other hand, although a protective role of essential elements was not found, Mg and Cu concentrations were higher in severe COVID-19 patients than in non-infected individuals.

Review on distribution, fate, and management of potentially toxic elements in incinerated medical wastes.

Medical wastes include all solid and liquid wastes that are produced during the treatment, diagnosis, and immunisation of animals and humans. A significant proportion of medical waste is infectious, hazardous, radioactive, and contains potentially toxic elements (PTEs) (i.e., heavy metal (loids)). PTEs, including arsenic (As), cadmium (Cd), lead (Pb) and mercury (Hg), are mostly present in plastic, syringes, rubber, adhesive plaster, battery wastes of medical facilities in elemental form, as well as oxides, chlorides, and sulfates. Incineration and sterilisation are the most common technologies adopted for the safe management and disposal of medical wastes, which are primarily aimed at eliminating deadly pathogens. The ash materials derived from the incineration of hazardous medical wastes are generally disposed of in landfills after the solidification/stabilisation (S/S) process. In contrast, the ash materials derived from nonhazardous wastes are applied to the soil as a source of nutrients and soil amendment. The release of PTEs from medical waste ash material from landfill sites and soil application can result in ecotoxicity. The present study is a review paper that aims to critically review the dynamisms of PTEs in various environmental media after medical waste disposal, the environmental and health implications of their poor management, and the common misconceptions regarding medical waste.

Using a Sensitivity Analysis and Spatial Clustering to Determine Vulnerability to Potentially Toxic Elements in a Semiarid City in Northwest Mexico

The Getis-Ord Gi* statistic clustering technique was used to create a hot spot exposure map using 14 potentially toxic elements (PTEs) found in urban dust samples in a semiarid city in northwest Mexico. The dust distribution and deposition in this city are influenced by the seasonal wind and rain from the North American Monsoon. The spatial clustering patterns of hot spots were used in combination with a sensitivity analysis to determine which variables most influenced the PTE hot spot exposure base map. The hot spots areas (%) were used as indicators of environmental vulnerability, and a final integrated map was selected to represent the highest vulnerability of PTEs with a 99% level of confidence. The results of the sensitivity analysis indicated that the flood zones and pervious and impervious zones were the most sensitive variables due to their weight in the spatial distribution. The hot spot areas were reduced by 60.4% by not considering these variables. The hot spot analysis resulted in an effective tool that allowed the combination of different spatial layers with specific characteristics to determine areas that present greater vulnerability to the distribution of PTEs, with impacts on public and environmental health.

Effect of the coronavirus pandemic lockdown to elemental composition of peat mosses.

Sphagnum mosses are used for biomonitoring air pollution. In 2019, samples were taken from two peat bogs areas in Germany and two in Slovenia to determine differences in their levels of potentially toxic elements (PTE). The Coronavirus Disease (COVID-19) lockdown caused a global decrease in air pollution. Therefore, we repeated the monitoring in 2020 to see if this was also reflected in moss composition. Despite the variability within bogs and the areas, it is possible to distinguish the degree of air pollution between the two countries. In comparison to 2019, the German mosses have higher contents of almost all elements and the Slovenian are enriched in Cr and Hg in 2020. Comparison of the PTE contents, their ratios to Sc, and the enrichment factors show that the COVID-19 lockdown led to a decrease in long-range pollutants bound to finest particles and increased the influence of local soil dusting. The effect prevailed over lower precipitation in 2020 compared to 2019. Transport and industry continued to contribute significantly to contamination. Sphagnum mosses proved to be good indicators of the spatial and temporal extent of pollution. Even relatively short periods of lower air pollution are reflected in moss PTE contents.

A comprehensive risk assessment of toxic elements in international brands of face foundation powders.

Despite the COVID-19 pandemic and wearing masks in many countries, women are keen on elegance, beauty and the use of face foundations. Assessment of health risks associated with the regular use of face foundation by females is dynamic due to the emerging products. The most common international 14 brands of face foundation powders were collected and the concentrations of different elements (Ag, Al, As, B, Ba, Be, Ca, Cd, Co, Cr, Cu, Fe, Hg, K, Li, Mg, Mn, Mo, Na, P, Pb, Sb, Se, Sn, V and Zn) in each sample were determined. A combined approach merging the conventional and computational tools was used for investigating the risk of exposure to toxic elements. Monte Carlo simulations were applied to calculate risks associated with twenty elements. We attempted different probability distribution functions for concentrations because the actual distribution functions are not known, and the only data available are the mean value and standard deviation of concentrations obtained from experiment. Our results indicate that the total non-carcinogenic health risk through exposure to different elements (Hazardous Index, HI) does not strongly depend on the choice of the probability distribution function for the concentrations. We also show that taking into account probability distributions of other variables and parameters such as body weight, exposed skin area, skin adhesion, etc. does not significantly change the main result rather just slightly broadening the final Hazardous Index distribution function. We found that calculated HI is well below unity for all considered samples, i.e., the dermal exposure to toxic elements in the considered facial powders is negligible and the considered face foundation powders are quite safe to use.